Single-Cell Sequencing for Precise Biological Insights :
Our sequencing technologies provide detailed genomic, transcriptomic, and epigenomic data from individual cells. We enable accurate studies of cell-to-cell variation in health and disease.
Who We Are ?
Single Nuclei specializes in single cell sequencing solutions for researchers analyzing complex biological systems. We deliver tools for high throughput sequencing that help study cellular differences with precision.
Our mission is to make single-cell data accessible and reliable for labs working in oncology, immunology, microbiology, neuroscience, and other fields.
Applications
Cancer Research
- Detects rare mutations and subclonal variations in tumors.
- Tracks tumor evolution and therapy resistance.
Immunology
- Profiles immune cell subpopulations in detail.
- Tracks responses to pathogens or therapies at a cellular level.
Developmental Biology
- Analyzes gene expression changes during cell differentiation.
- Maps developmental trajectories in embryos.
Microbiology
- Identifies genetic and functional diversity in microbial populations.
- Investigates host-pathogen interactions with single-cell resolution.
Neuroscience
- Dissects the molecular profiles of distinct neuron types.
- Links gene expression to neuronal activity.
Technology
Single-Cell Sequencing Methods
- Genome Sequencing
- Detects mutations, structural variants, and copy number changes at the cellular level.
- Transcriptomics
- Quantifies RNA expression in individual cells to characterize cell states and identities.
- Epigenomics
- Maps DNA accessibility and chromatin modifications, revealing gene regulatory mechanisms.
- Multi-Omics Analysis
- Integrates genomic, transcriptomic, and epigenomic data to provide a complete view of cellular function.
Our platform ensures high accuracy, reproducibility, and scalability for research applications